Products for Research Use Only
RegisterLogin

SHMT1 Antibody

CAT: 0223-57-723Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-57-723Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
NCBI Gene ID
6470
Swiss Prot
P34896
Accession Number
P34896
Host
Rabbit
Reactivity
Human
Immunogen
This SHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human SHMT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
SHMT1
NCBI Official Name
Serine hydroxymethyltransferase, cytosolic
NCBI Organism
Homo sapiens
Background Reference 01
Porter, K.E., et al. Environ. Res. 110 (6) :580-587 (2010)
Background Reference 02
Summers, C.M., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (8) :679-688 (2010)
Background Reference 03
Vijayakrishnan, J., et al. Haematologica 95 (8) :1405-1414 (2010)
Background Reference 04
Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19 (7) :1812-1821 (2010)
Other Product Names
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase, SHMT1
Tested Applications
WB, IHC-P
Protein ID
462184
Physical Properties
Liquid

Related Products

CatalogName
91-687SHMT1 Recombinant Protein
30-163SHMT2 Antibody
14-280SHMT2 Antibody
30-164SHMT2 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody

Alternative Products

CatalogName
GTR18135674SHMT1 Antibody

Popular Products