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ARRB1 Antibody [F7C2]

CAT: 0223-13-780Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-13-780Size:100 µL
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Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
NCBI Gene ID
408
Swiss Prot
P49407
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ARRB1
Clonality
Monoclonal
Clone
[F7C2]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
PC-12
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 47kDa
Fragment
IgG
Symbol
ARRB1
Positive Control 2
Jurkat
NCBI Official Name
Beta-arrestin-1
NCBI Organism
Homo sapiens
Other Product Names
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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