Products for Research Use Only
RegisterLogin

ARRB1 Antibody

CAT: 0223-56-170Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-170Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
NCBI Gene ID
408
Swiss Prot
P49407
Accession Number
P49407
Host
Rabbit
Reactivity
Human
Immunogen
This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
ARRB1
NCBI Official Name
Beta-arrestin-1
NCBI Organism
Homo sapiens
Background Reference 01
Shukla, A.K., et al. J. Biol. Chem. 285 (39) :30115-30125 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Lee, D.K., et al. Biochem. Biophys. Res. Commun. 395 (2) :185-189 (2010)
Background Reference 04
Kim, J.I., et al. Mol. Cancer Res. 8 (4) :569-577 (2010)
Other Product Names
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
20141238
Physical Properties
Liquid

Related Products

CatalogName
30-345ARRB2 Antibody
14-883ARRB2 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody

Alternative Products

CatalogName
70R-15848ARRB1 antibody

Popular Products