COL11A2 Antibody

CAT: 0223-13-674Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-674Size:100 µL
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Background
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53) . Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
NCBI Gene ID
1302
Swiss Prot
P13942
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_542411.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
A375
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 150kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
COL11A2
Positive Control 2
HepG2
Positive Control 3
K-562
NCBI Official Name
Collagen, type XI, alpha 2
NCBI Organism
Homo sapiens
Other Product Names
COL11A2, collagen, type XI, alpha 2, DAQB-79P13.8, HGNC:2187, DFNA13, HKE5, PARP, STL3, Collagen alpha 2 (XI), FBCG2, DFNB53
Tested Applications
WB
Physical Properties
Liquid

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