COL17A1 Antibody

• Background:

  COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.

• NCBI Gene ID:

  1308

• Swiss Prot:

  Q9UMD9

• Accession Number:

  Q9UMD9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COL17A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 475-504 amino acids from the Central region of human COL17A1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  150 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  COL17A1

• NCBI Official Name:

  Collagen alpha-1 (XVII) chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Di Zenzo, G., et.al., J. Invest. Dermatol. 130 (4), 1040-1047 (2010)

• Background Reference 02:

  Ujiie, H., et.al., J. Immunol. 184 (4), 2166-2174 (2010)

• Other Product Names:

  Collagen alpha-1 (XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120 kDa linear IgA disease antigen, 120 kDa linear IgA dermatosis antigen, Linear IgA disease antigen 1, LAD-1, 97 kDa linear IgA disease antigen, 97 kDa linear IgA bullous dermatosis antigen, 97 kDa LAD antigen, 97-LAD, Linear IgA bullous disease antigen of 97 kDa, LABD97, COL17A1, BP180, BPAG2

• Tested Applications:

  WB, Flow

• Protein ID:

  146345399

• Physical Properties:

  Liquid