TRPM7 Antibody

• Background:

  The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants.

• NCBI Gene ID:

  54822

• Swiss Prot:

  Q96QT4

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 756-855 of human TRPM7 (NP_060142.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse skeletal muscle

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 230kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  TRPM7

• NCBI Official Name:

  Transient receptor potential cation channel, subfamily M, member 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TRPM7, transient receptor potential cation channel, subfamily M, member 7, CHAK, CHAK1, LTRPC7, FLJ20117, TRP-PLIK, LTRPC ion channel family member 7, homolog of mouse transient receptor potential-phospholipase C-interacting kinase CHaK hypothetical protein FLJ20117

• Tested Applications:

  WB

• Physical Properties:

  Liquid