TRPM4 Antibody

CAT: 0223-58-239Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-239Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
54795
Swiss Prot
Q8TD43
Accession Number
Q8TD43
Host
Rabbit
Reactivity
Human
Immunogen
This TRPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1121-1149 amino acids from the C-terminal region of human TRPM4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
134 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TRPM4
NCBI Official Name
Transient receptor potential cation channel subfamily M member 4
NCBI Organism
Homo sapiens
Background Reference 01
Liu, H., et al. Circ Cardiovasc Genet 3 (4) :374-385 (2010)
Background Reference 02
Yoo, J.C., et al. Biochem. Biophys. Res. Commun. 391 (1) :806-811 (2010)
Background Reference 03
Kruse, M., et al. J. Clin. Invest. 119 (9) :2737-2744 (2009)
Background Reference 04
Marigo, V., et al. Mol. Cell. Endocrinol. 299 (2) :194-203 (2009)
Other Product Names
Transient receptor potential cation channel subfamily M member 4, hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC-4, LTrpC4, Melastatin-4, TRPM4, LTRPC4
Tested Applications
WB
Protein ID
74715868
Physical Properties
Liquid

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