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TRPM2 Antibody

CAT: 0223-25-953Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-953Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
7226
Swiss Prot
O94759
Accession Number
NP_003298
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRPM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRPM2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
171 kDa
Applications Notes
TRPM2 antibody can be used for detection of TRPM2 by ELISA at 1:62500. TRPM2 antibody can be used for detection of TRPM2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TRPM2
NCBI Official Name
Transient receptor potential cation channel, subfamily M, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Hecquet, C.M., (2008) Circ. Res. 102 (3), 347-355.
Other Product Names
TRPM2, EREG1, KNP3, LTRPC2, MGC133383, NUDT9H, NUDT9L1, TRPC7
Tested Applications
ELISA, WB
Protein ID
4507689
Physical Properties
Liquid

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