TRPM2 Antibody

• Background:

  TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• NCBI Gene ID:

  7226

• Swiss Prot:

  O94759

• Accession Number:

  NP_003298

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRPM2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRPM2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  171 kDa

• Applications Notes:

  TRPM2 antibody can be used for detection of TRPM2 by ELISA at 1:62500. TRPM2 antibody can be used for detection of TRPM2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TRPM2

• NCBI Official Name:

  Transient receptor potential cation channel, subfamily M, member 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hecquet, C.M., (2008) Circ. Res. 102 (3), 347-355.

• Other Product Names:

  TRPM2, EREG1, KNP3, LTRPC2, MGC133383, NUDT9H, NUDT9L1, TRPC7

• Tested Applications:

  ELISA, WB

• Protein ID:

  4507689

• Physical Properties:

  Liquid