MST1R Antibody

• Background:

  This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

• NCBI Gene ID:

  4486

• Swiss Prot:

  Q04912

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human MST1R

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse lung

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 145kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:1000

• Symbol:

  MST1R

• NCBI Official Name:

  Macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MST1R, C-met-related tyrosine kinase, CD136, CDw136, CD136 antigen, Friend virus susceptibility 2, Fv2, MSP receptor, p185-Ron, PTK8 protein tyrosine kinase 8, RON, Soluble RON variant 3, Soluble RON variant 1, MST1R variant RON30, Oncogene RON, PTK8, MST1R variant RON62, Protein-tyrosine kinase 8, RON variant E2E3, Soluble RON variant 2, Soluble RON variant 4

• Tested Applications:

  WB

• Physical Properties:

  Liquid