Products for Research Use Only

MST1 Antibody

CAT: 0223-63-289Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-289Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
NCBI Gene ID
6789
Swiss Prot
Q13043
Accession Number
Q13043
Host
Rabbit
Reactivity
Human
Immunogen
This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
STK4
NCBI Official Name
Serine/threonine-protein kinase 4
NCBI Organism
Homo sapiens
Background Reference 01
Cheung, W.L., et al., Cell 113 (4) :507-517 (2003) .
Background Reference 02
Lin, Y., et al., J. Biol. Chem. 277 (50) :47991-48001 (2002) .
Background Reference 03
De Souza, P.M., et al., Blood 99 (9) :3432-3438 (2002) .
Background Reference 04
Ura, S., et al., Proc. Natl. Acad. Sci. U.S.A. 98 (18) :10148-10153 (2001) .
Other Product Names
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1
Tested Applications
WB, IHC-P
Protein ID
13124559
Physical Properties
Liquid