MST1 Antibody

• Background:

  The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

• NCBI Gene ID:

  4485

• Swiss Prot:

  P26927

• Accession Number:

  P26927

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human MST1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MST1

• NCBI Official Name:

  Hepatocyte growth factor-like protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Latiano, A., et al. Inflamm. Bowel Dis. 16 (7) :1108-1117 (2010)

• Background Reference 02:

  Morgan, A.R., et al. Hum. Immunol. 71 (6) :602-609 (2010)

• Background Reference 03:

  Qiao, M., et al. Mol. Cell 38 (4) :512-523 (2010)

• Background Reference 04:

  McGovern, D.P., et al. Nat. Genet. 42 (4) :332-337 (2010)

• Other Product Names:

  Hepatocyte growth factor-like protein, Macrophage stimulatory protein, Macrophage-stimulating protein, MSP, Hepatocyte growth factor-like protein alpha chain, Hepatocyte growth factor-like protein beta chain, MST1, D3F15S2, DNF15S2, HGFL

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  147744563

• Physical Properties:

  Liquid