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BCL2A1 Antibody

CAT: 0223-13-046Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-13-046Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
597
Swiss Prot
Q16548
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human BCL2A1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology
Purification
Affinity purification
Positive Control
Mouse lung
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 20kDa
Fragment
IgG
Symbol
BCL2A1
NCBI Official Name
BCL2-related protein A1
NCBI Organism
Homo sapiens
Other Product Names
Bfl-1 Antibody: GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5, GRS, Bcl-2-related protein A1, Bcl-2-like protein 5, Bcl2-L-5
Tested Applications
WB, IHC, Flow
Physical Properties
Liquid

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