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WDR12 Antibody

CAT: 0223-56-836Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-836Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.
NCBI Gene ID
55759
Swiss Prot
Q9GZL7
Accession Number
Q9GZL7
Host
Rabbit
Reactivity
Human
Immunogen
This WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human WDR12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
WDR12
NCBI Official Name
Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
NCBI Organism
Homo sapiens
Background Reference 01
Kathiresan, S., et al. Nat. Genet. 41 (3) :334-341 (2009)
Background Reference 02
Rohrmoser, M., et al. Mol. Cell. Biol. 27 (10) :3682-3694 (2007)
Background Reference 03
Higa, L.A., et al. Nat. Cell Biol. 8 (11) :1277-1283 (2006)
Background Reference 04
Grimm, T., et al. Nucleic Acids Res. 34 (10) :3030-3043 (2006)
Other Product Names
Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}, WD repeat-containing protein 12 {ECO:0000255|HAMAP-Rule:MF_03029}, WDR12 {ECO:0000255|HAMAP-Rule:MF_03029}
Tested Applications
WB, IHC-P
Protein ID
20140802
Physical Properties
Liquid

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