Products for Research Use Only
RegisterLogin

Lin28 Antibody

CAT: 0223-5605-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-5605-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Lin28 Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
NCBI Gene ID
79727
Swiss Prot
Q9H9Z2
Accession Number
EAX07814
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Lin28 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1207 - Raji Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (87%), Chicken: (79%)
Buffer
Lin28 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Lin28 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
LIN28A
Positive Control 2
Cat. No. 10-901 - Human Spleen Tissue Slide
NCBI Official Name
Lin-28 homolog (C. elegans)
NCBI Organism
Homo sapiens
Background Reference 01
Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell1989; 57:49-57.
Background Reference 02
Carpenter MK, Rosler E, and Rao MS. Characterization and differentiation of human embryonic stem cells. Cloning Stem Cells2003; 5:79-88.
Background Reference 03
Tyu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science2007; 318:1917-20
Background Reference 04
Okita K, Nakagawa M, Hyenjong H, et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science2008; 322:949-53.
Other Product Names
Lin28 Antibody: CSDD1, LIN28, LIN-28, ZCCHC1, lin-28A, CSDD1, Protein lin-28 homolog A, Zinc finger CCHC domain-containing protein 1, Lin-28A
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
119628219
Physical Properties
Liquid

Related Products

CatalogName
5605PLin28 Peptide
40-562-0005mgLin28-TAT Recombinant Protein
40-562-01Lin28-TAT Recombinant Protein
40-562-0025mgLin28-TAT Recombinant Protein
70-948LIN28B Antibody
58-047LIN28B Antibody
79-728LIN28B Antibody
58-046LIN28B Antibody
64-160WAS Antibody
60-596WAS Antibody

Alternative Products

CatalogName
20R-2501Lin28 antibody

Popular Products