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CP-220629

CAT: 0804-HY-129785Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129785Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg) [1].
CAS Number
162141-96-0
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cp-220629.html
Smiles
O=C1C(N(C2CCCC2)N=C3CC)=C3CCN1C4=CC=CC=C4C
Molecular Formula
C20H25N3O
Molecular Weight
323.43
References & Citations
[1]A J Duplantier, et al. 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as novel inhibitors of human eosinophil phosphodiesterase. J Med Chem. 1998 Jun 18;41 (13) :2268-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4

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