CP-220629

• Description:

  CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg) [1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cp-220629.html

• Smiles:

  O=C1C (N (C2CCCC2) N=C3CC) =C3CCN1C4=CC=CC=C4C

• Molecular Formula:

  C20H25N3O

• Molecular Weight:

  323.43

• References & Citations:

  [1]A J Duplantier, et al. 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as novel inhibitors of human eosinophil phosphodiesterase. J Med Chem. 1998 Jun 18;41 (13) :2268-77.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PDE4

• CAS Number:

  162141-96-0