CP-220629

• Description :

  CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg) [1].

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cp-220629.html

• Smiles :

  O=C1C(N(C2CCCC2)N=C3CC)=C3CCN1C4=CC=CC=C4C

• Molecular Formula :

  C20H25N3O

• Molecular Weight :

  323.43

• References & Citations :

  [1]A J Duplantier, et al. 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as novel inhibitors of human eosinophil phosphodiesterase. J Med Chem. 1998 Jun 18;41 (13) :2268-77.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PDE4

• CAS Number :

  [162141-96-0]