MUT Rabbit pAb (APR25369N)

CAT: 0882-APR25369N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR25369N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MUT Rabbit pAb (APR25369N) .

Synonyms

MUT; MCM

Gene ID

4594

UniProt

P22033

Cellular Locus

Mitochondrion matrix

Dilution

WB 1:1000 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 83kDa Observed MW: 83kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4594

Uniprot URL

https://www.uniprot.org/uniprot/P22033

AA Sequence

EMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV

UniProtKB · P22033

Methylmalonyl-CoA mutase, mitochondrial

MUTA_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P22033
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MMUT
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: MCM
EC number: 5.4.99.2
Processing: Precursor
Secondary accessions: A8K953, Q5SYZ3, Q96B11, Q9UD64

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Ligand

CobalaminCobaltMetal-binding

Cellular component

CytoplasmMitochondrion

Disease

Disease variant

Molecular function

Isomerase

Domain

Transit peptide

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