EED Rabbit pAb (APR19393N)

CAT: 0882-APR19393N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19393N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EED Rabbit pAb (APR19393N) .

Synonyms

EED; HEED; WAIT1

Gene ID

8726

UniProt

O75530

Cellular Locus

Chromosome, Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 45kDa/50kDa/53kDa Observed MW: 65kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8726

Uniprot URL

https://www.uniprot.org/uniprot/O75530

AA Sequence

MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQ

UniProtKB · O75530

Polycomb protein EED

EED_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O75530
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EED
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: hEED
EC number: —
Processing: —
Secondary accessions: A8K7V5, O00149, Q6NTH2, Q7LDA5, Q7LDG8, Q86VV2, Q9UNY7

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative initiationAlternative splicing

Molecular function

Chromatin regulatorRepressor

Cellular component

ChromosomeNucleus

Disease

Disease variant

Biological process

Host-virus interactionTranscriptionTranscription regulation

Domain

RepeatWD repeat

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