Products for Research Use Only

HFE Rabbit mAb (AMR11368N)

CAT: 0882-AMR11368N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-AMR11368N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M) . It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HFE Rabbit mAb (AMR11368N) .
Synonyms
HFE; HFE1; HH; HLA-H; MVCD7; TFQTL2; hemochromatosis
Gene ID
3077
UniProt
Q30201
Cellular Locus
Cell membrane, Single-pass type I membrane protein
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 40kDa Observed MW: 45KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3077
Uniprot URL
https://www.uniprot.org/uniprot/Q30201
AA Sequence
Email for sequence