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ARD-2585

CAT: 0804-HY-139436-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-139436-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor[1].
CAS Number
[2757422-79-8]
UNSPSC
12352005
Target
Androgen Receptor; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ard-2585.html
Purity
99.16
Solubility
DMSO : 85 mg/mL (ultrasonic)
Smiles
O=C(N(C1C(NC(CC1)=O)=O)C2=O)C(C2=C3)=CC=C3N(C4)CC4N(CC5)CCN5C(C=C6)=CC=C6C(N[C@@H]7CC[C@@H](N(C)C8=CC=C(C#N)C(Cl)=C8)CC7)=O
Molecular Formula
C41H43ClN8O5
Molecular Weight
763.28
References & Citations
[1]Weiguo Xiang. et al. Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer. J Med Chem. 2021 Sep 23;64 (18) :13487-13509.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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