PDE4B-IN-3

PDE4B-IN-3

• CAS Number: 2819779-01-4
• UNSPSC Description: PDE4B-IN-3 is a potent PDE4B inhibitor with an IC50 of 0.94 μM. PDE4B-IN-3 has anti-inflammatory activities[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pde4b-in-3.html
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: CC(C1=CC(C(C)C)=C(C(C(C)C)=C1)S(=O)(NC2=CC(NS(=O)(C3=CC=CC4=CC=CN=C43)=O)=CC=C2)=O)C
• Molecular Weight: 565.75
• References & Citations: [1]Siqi Xing, et al. Novel quinoline-based derivatives: A new class of PDE4B inhibitors for adjuvant-induced arthritis. Eur J Med Chem. 2022 Aug 5;238:114497.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported