GPX4-IN-4
CAT:
804-HY-149923-06
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GPX4-IN-4
- CAS Number: 2920221-53-8
- UNSPSC Description: GPX4-IN-4 (Compound 24) is a potent GPX4 inhibitor. GPX4-IN-4 can be used for the research of cancer[1].
- Target Antigen: Glutathione Peroxidase
- Type: Reference compound
- Related Pathways: Apoptosis;Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/gpx4-in-4.html
- Solubility: DMSO : 200 mg/mL (ultrasonic)
- Smiles: COC([C@H]1CC2=C([C@@H](N1C(CCl)=O)C3=CC=C(C=C3)S(C)(=O)=O)NC4=CC=CC=C42)=O
- Molecular Weight: 460.93
- References & Citations: [1]Randolph JT, et al. Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo. J Med Chem. 2023 Mar 23;66(6):3852-3865.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported