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AP2S1 rabbit pAb

CAT: 0855-ES18307-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES18307-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Description
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
UniProt
P53680
Swiss Prot
P53680
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human AP2S1 AA range: 26-76
Target
AP2S1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. .
Gene ID (Human)
1175

UniProtKB · P53680

AP-2 complex subunit sigma

AP2S1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P53680
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AP2S1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R4Z4, O75977, Q6PK67
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCoated pitMembrane

Disease

Disease variant

Biological process

EndocytosisProtein transportTransport

PTM

Phosphoprotein

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