MitoBloCK-11

• Description:

  MitoBloCK-11 is a new small molecule with a protein-binding target, Seo1. MitoBloCK-11 plays an important role in the delivery of PINK1 pathway. MitoBloCK-11 can be used in the study of autosomal recessive Parkinson's disease[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PINK1/Parkin

• Type:

  Reference compound

• Related Pathways:

  Autophagy; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mitoblock-11.html

• Purity:

  99.28

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C (N/N=C/C1=CC=C ([N+] ([O-]) =O) S1) COC2=C3C=CC=CC3=C (Br) C=C2

• Molecular Formula:

  C17H12BrN3O4S

• Molecular Weight:

  434.26

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Conti Michael, et al. Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy.2018.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  413606-16-3