MitoBloCK-11

• Description :

  MitoBloCK-11 is a new small molecule with a protein-binding target, Seo1. MitoBloCK-11 plays an important role in the delivery of PINK1 pathway. MitoBloCK-11 can be used in the study of autosomal recessive Parkinson's disease[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PINK1/Parkin

• Type :

  Reference compound

• Related Pathways :

  Autophagy; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/mitoblock-11.html

• Purity :

  99.28

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(N/N=C/C1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2

• Molecular Formula :

  C17H12BrN3O4S

• Molecular Weight :

  434.26

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Conti Michael, et al. Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy.2018.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [413606-16-3]