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MitoBloCK-12

CAT: 0498-bs-82303C-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82303C-01Size:50 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Attenuates mitochondrial protein import (4-10 M) . Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
RT

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