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3-Methylxanthine

CAT: 0804-HY-50723-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:0804-HY-50723-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
CAS Number
1076-22-8
UNSPSC
12352005
Hazard Statement
H302
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-Methylxanthine.html
Purity
99.78
Solubility
1M NaOH : 50 mg/mL (ultrasonic; adjust pH to 11 with 1M NaOH) |DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL
Smiles
O=C1N(C)C2=C(N=CN2)C(N1)=O
Molecular Formula
C6H6N4O2
Molecular Weight
166.14
Precautions
H302
References & Citations
[1]Tanaka H, et al. Inhibition of cyclic GMP phosphodiesterase by xanthine derivatives relaxes guinea-pig trachealis smooth muscle. Clin Exp Pharmacol Physiol. 1991 Mar;18 (3) :163-8.|[2]Yamamoto K, et al. Neurotoxic convulsions induced by theophylline and its metabolites in mice. Biol Pharm Bull. 1996 Jun;19 (6) :869-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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