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1-Methylxanthine

CAT: 0804-HY-W008449-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W008449-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) [1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].
CAS Number
6136-37-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-methylxanthine.html
Concentration
10mM
Purity
99.46
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1C)NC2=C(N=CN2)C1=O
Molecular Formula
C6H6N4O2
Molecular Weight
166.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Algharrawi KH, et al. Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli. Microb Cell Fact. 2015 Dec 21;14:203.|[2]Youn H, et al. 1-Methylxanthine enhances the radiosensitivity of tumor cells. Int J Radiat Biol. 2009 Feb;85 (2) :167-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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