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7-Methylxanthine

CAT: 0804-HY-W017163-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W017163-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity[1][2].
CAS Number
552-62-5
UNSPSC
12352005
Hazard Statement
H302
Target
Adenosine Receptor; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/7-Methyl-1H-purine-2,6_3H,7H_-dione.html
Purity
99.94
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1C=NC2=C1C(=O)NC(=O)N2
Molecular Formula
C6H6N4O2
Molecular Weight
166.14
Precautions
H302
References & Citations
[1]Caubet MS, et al. Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. J Pharm Biomed Anal. 2004 Feb 4;34 (2) :379-89.|[2]Hung LF, et al. The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci. 2018 Jan 1;59 (1) :472-486.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Human Endogenous Metabolite