7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9)

7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9)

• UNSPSC Description: 7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9) is the 13C and 15N labeled 7-Methylxanthine[1]. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi[2].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/7-methylxanthine-2-4-5-6-13c4-1-3-15n2-with-variable-15n-labeling-at-n9.html
• Solubility: 10 mM in DMSO
• Smiles: O=[13C]1[15NH][13C]([13C]2=[13C]([15NH]1)[R]=CN2C)=O
• Molecular Weight: 158.09
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Caubet MS, et al. Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. J Pharm Biomed Anal. 2004 Feb 4;34(2):379-89.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported