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SAHM1 (TFA)

CAT: 0804-HY-P2203ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P2203ASize:1 Each
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Description
SAHM1 TFA is a Notch pathway inhibitor. SAHM1 TFA stabilizes hydrocarbon-stapled alpha helical peptide. SAHM1 TFA targets the protein-protein interface and prevents Notch complex assembly.
UNSPSC
12352209
Target
Notch
Type
Peptides
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sahm1-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@]2(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@](C)(CCC/C=C/CCC2)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC(CCNC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)CS)=O)CCCNC(N)=N)=O)C)=O)CC3=CN=CN3)=O)=O)=O
Molecular Formula
C96H163N36F3O25S
Molecular Weight
2310.60
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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