Acetophenazine (dimaleate)

CAT: 0804-HY-B1262-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1262-01Size:5 mg
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Description
Acetophenazine dimaleate, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].
CAS Number
[5714-00-1]
UNSPSC
12352005
Hazard Statement
H319
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Acetophenazine_dimaleate.html
Purity
99.90
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(C(C=C1N2CCCN3CCN(CCO)CC3)=CC=C1SC4=C2C=CC=C4)=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Molecular Formula
C31H37N3O10S
Molecular Weight
643.70
Precautions
H319
References & Citations
[1]Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24 (3) :273-8.|[2]Azam Bazrafshan, et al. Acetophenazine versus chlorpromazine for schizophrenia. Cochrane Database of Systematic Reviews. 2015, Issue 4.|[3]KNIGHT WR, HOLTZ JR, SPROGIS GR. ACETOPHENAZINE AND FIGHTING BEHAVIOR IN MICE. Science. 1963 Aug 30;141 (3583) :830-1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D2 Receptor

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