Acetophenazine

• Description:

  Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H312, H332

• Target:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/acetophenazine.html

• Purity:

  98.05

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C1=CC=C(SC2=C3C=CC=C2)C(N3CCCN4CCN(CC4)CCO)=C1)=O

• Molecular Formula:

  C23H29N3O2S

• Molecular Weight:

  411.56

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Azam Bazrafshan, et al. Acetophenazine versus chlorpromazine for schizophrenia. Cochrane Database of Systematic Reviews. 2015, Issue 4.|[2]Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24 (3) :273-8.|[3]KNIGHT WR, HOLTZ JR, SPROGIS GR. ACETOPHENAZINE AND FIGHTING BEHAVIOR IN MICE. Science. 1963 Aug 30;141 (3583) :830-1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  D2 Receptor

• CAS Number:

  [2751-68-0]