Acetophenazine

• UNSPSC Description:

  Acetophenazine, a phenothiazine derivative, is an antipsychotic agent. Acetophenazine primarily blocks dopamine D2 receptors in the brain. Acetophenazine can be used for researching psychotic disorders such as schizophrenia and anxious depression[1][2].

• Target Antigen:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/acetophenazine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(SC2=C3C=CC=C2)C(N3CCCN4CCN(CC4)CCO)=C1)=O

• Molecular Weight:

  411.56

• References & Citations:

  [1]Azam Bazrafshan, et al. Acetophenazine versus chlorpromazine for schizophrenia. Cochrane Database of Systematic Reviews. 2015, Issue 4.|[2]Hollister LE, et al. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24(3):273-8.|[3]KNIGHT WR, HOLTZ JR, SPROGIS GR. ACETOPHENAZINE AND FIGHTING BEHAVIOR IN MICE. Science. 1963 Aug 30;141(3583):830-1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  2751-68-0