Prochlorperazine (dimaleate)
CAT:
804-HY-B0807A-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Prochlorperazine (dimaleate)
- CAS Number: 84-02-6
- UNSPSC Description: Prochlorperazine dimaleate is a first-generation antipsychotic. Prochlorperazine dimaleate can be used in the research of chemotherapy-induced nausea and vomiting (CINV). Prochlorperazine dimaleate also possesses anticancer activity. Prochlorperazine dimaleate exhibits IC50 values of 6.4 μM, 4.5 μM and 2.3 μM for NOX1, NOX2 and NOX5, respectively[1][2].
- Target Antigen: NADPH Oxidase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/prochlorperazine-dimaleate.html
- Purity: 98.0
- Smiles: O=C(O)/C=C\C(O)=O.CN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(Cl)C=C24)CC1.O=C(O)/C=C\C(O)=O
- Molecular Weight: 606.09
- References & Citations: [1]Melissa Lau Moon Lin, et al. The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis. Drug Saf. 2016 Jun;39(6):509-16.|[2]Michał Otręba, et al. In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review. J Appl Toxicol. 2021 Jan;41(1):82-94.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, stored under nitrogen)
- Clinical Information: Launched