Azatadine (dimaleate)

Azatadine (dimaleate)

• CAS Number: 3978-86-7
• UNSPSC Description: Azatadine bimaleate is an inhibitor of histamine receptors and choline receptors with IC50s of 6.5 nM and 10 nM respectively.
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Endocrinology
• Assay Protocol: https://www.medchemexpress.com/Azatadine-dimaleate.html
• Purity: 99.85
• Solubility: DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
• Smiles: O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O.CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C4\2
• Molecular Weight: 522.55
• References & Citations: [1]Wilson JD, et al. Azatadine maleate (Zadine): evaluation in the management of allergic rhinitis. N Z Med J. 1981 Aug 12;94(689):79-81.|[2]Tozzi S, et al. The pharmacology of azatadine, a potential antiallergy drug. Agents Actions. 1974 Oct;4(4):264-70.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched