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HOKU-81

CAT: 0804-HY-50291-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-50291-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol. HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].
CAS Number
58020-43-2
Product Name Alternative
4-Hydroxytulobuterol
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/HOKU-81.html
Purity
95.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC1=C(C(O)CNC(C)(C)C)C=CC(O)=C1
Molecular Formula
C12H18ClNO2
Molecular Weight
243.73
Precautions
H302, H312, H332
References & Citations
[1]Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1- (2-chloro-4-hydroxyphenyl) -2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30 (8) :1272-8.|[2]Gomi Y, Shirahase H, Funato H. Effects of 1- (2-chloro-4-hydroxyphenyl) -t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29 (4) :515-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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