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Recombinant Human MKI67 Protein

CAT: 0763-PDEH100743-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0763-PDEH100743-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226)
Abbreviation
MKI67
Synonyms
Antigen KI-67; Antigen Ki67; Antigen identified by monoclonal antibody Ki-67; Proliferation marker protein Ki-67
UniProt
P46013
Accession Number
P46013
Expression System
E.coli
Tag
N-His
Sequence
Met1-Pro120
Field of Research
Cancer; Cell Biology; Neuroscience; Tags & Cell Markers
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
13.8 kDa
Observed Molecular Weight
14 kDa
Species
Human

UniProtKB · P46013

Proliferation marker protein Ki-67

KI67_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46013
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MKI67
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5VWH2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycle

Cellular component

ChromosomeNucleus

Molecular function

DNA-binding

Domain

Repeat

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