MK-8876

• Description :

  MK-8876 is an inhibitor of HCV NS5b site D, which can be used in the research of hepatitis C virus [1][2].

• UNSPSC :

  12352005

• Target :

  HCV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/mk-8876.html

• Smiles :

  O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(C)S(=O)(C)=O)=C(C4=CC=C5C(C(N6CO5)=CC7=C6C=CC=C7F)=N4)C=C13)NC

• Molecular Formula :

  C32H24F2N4O5S

• Molecular Weight :

  614.62

• References & Citations :

  [1]McLaughlin M, Dermenjian R K, Jin Y, et al. Evaluation and control of mutagenic impurities in a development compound: purge factor estimates vs measured amounts[J]. Organic Process Research & Development, 2015, 19 (11) : 1531-1535.|[2]Williams M J, et al. Process Development of the HCV NS5B Site D Inhibitor MK-8876[J]. Organic Process Research & Development, 2016, 20 (7) : 1227-1238.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [1426960-33-9]