MK-8876

• UNSPSC Description:

  MK-8876 is an inhibitor of HCV NS5b site D, which can be used in the research of hepatitis C virus [1][2].

• Target Antigen:

  HCV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mk-8876.html

• Smiles:

  O=C(C1=C(C2=CC=C(F)C=C2)OC3=CC(N(C)S(=O)(C)=O)=C(C4=CC=C5C(C(N6CO5)=CC7=C6C=CC=C7F)=N4)C=C13)NC

• Molecular Weight:

  614.62

• References & Citations:

  [1]McLaughlin M, Dermenjian R K, Jin Y, et al. Evaluation and control of mutagenic impurities in a development compound: purge factor estimates vs measured amounts[J]. Organic Process Research & Development, 2015, 19(11): 1531-1535.|[2]Williams M J, et al. Process Development of the HCV NS5B Site D Inhibitor MK-8876[J]. Organic Process Research & Development, 2016, 20(7): 1227-1238.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  1426960-33-9