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SEH inhibitor-7

CAT: 0804-HY-148136-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148136-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation[1].
CAS Number
340221-20-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-7.html
Purity
99.50
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=C(OC)C=C1)CC2CCCCC2
Molecular Formula
C15H21NO2
Molecular Weight
247.33
Precautions
H302, H315, H319
References & Citations
[1]Kim IH, et al. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. J Med Chem. 2005 May 19;48 (10) :3621-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2-cyclohexyl-N-(4-methoxyphenyl)acetamide
CAS Number340221-20-7
PubChem CID880925
IUPAC Name2-cyclohexyl-N-(4-methoxyphenyl)acetamide
Molecular FormulaC15H21NO2
Molecular Weight247.33
XLogP3.7
Topological Polar Surface Area38.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Heavy Atom Count18
Formal Charge0
Complexity253
SMILES
COC1=CC=C(C=C1)NC(=O)CC2CCCCC2
InChI
InChI=1S/C15H21NO2/c1-18-14-9-7-13(8-10-14)16-15(17)11-12-5-3-2-4-6-12/h7-10,12H,2-6,11H2,1H3,(H,16,17)
InChIKey
SCFJMQSXUCFKPS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-cyclohexyl-N-(4-methoxyphenyl)acetamide
CAS: 340221-20-7
CID: 880925
Formula: C15H21NO2
MW: 247.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight247.33
XLogP33.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass247.157228913
Monoisotopic Mass247.157228913
Topological Polar Surface Area38.3 Ų
Heavy Atom Count18
Formal Charge0
Complexity253
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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