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SEH inhibitor-4

CAT: 0804-HY-147732Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147732Size:1 Each
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Description
Intensive structural modification resulted in the identification of compound B15 as an effective sEH inhibitor with a value of 0.03 ± 0.01 nm, and the presence of soluble epoxide hydrolase (SEH) can reduce inflammation and pain.
CAS Number
2851838-08-7
UNSPSC
12352005
Target
Epoxide Hydrolase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-4.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C=CC(C(NC2=CC=C(C=C2)Cl)=O)=C1)N(C(NC3=CC=C(C=C3)Cl)=O)CCN4CCOCC4
Molecular Formula
C27H28Cl2N4O3
Molecular Weight
527.44
References & Citations
[1]Tian Y, et al. Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors. Bioorg Med Chem Lett. 2022 Aug 15;70:128805.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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