NP-313

• UNSPSC Description:

  NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca2+ inward flow[1].

• Target Antigen:

  Thrombin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/np-313.html

• Purity:

  99.58

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  CC(NC(C1=O)=C(Cl)C(C2=C1C=CC=C2)=O)=O

• Molecular Weight:

  249.65

• References & Citations:

  [1]Heng-Lan Kuo, et al. NP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry. Br J Pharmacol. 2011 Apr;162(8):1871-83.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  5397-78-4