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SHP504

CAT: 0804-HY-125259-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125259-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP504 is a SHP2 phosphatase inhibitor, with an IC50 of 21 μM for SHP21–525[1].
CAS Number
2222280-83-1
UNSPSC
12352005
Target
Phosphatase; SHP2
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp504.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(O)C(C2=NN=C(N3CC4=CC=CC=C4Cl)N2C5=C(C=CC=C5)C3=O)=C1
Molecular Formula
C23H15ClN4O4
Molecular Weight
446.84
References & Citations
[1]Michelle Fodor, et al. Dual Allosteric Inhibition of SHP2 Phosphatase. ACS Chem Biol. 2018 Mar 16;13 (3) :647-656.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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