Products for Research Use Only
RegisterLogin

SHP504

CAT: 0013-GTR19185937-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19185937-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SHP504 is a cell-permeable small molecule inhibitor of SHP2 phosphatase, demonstrating an IC50 of 21 μM against the recombinant SHP21-525 protein. It is a valuable research tool for investigating SHP2-dependent signaling pathways in cancer and developmental biology, applicable in both cellular and biochemical assays.
CAS Number
2222280-83-1
Field of Research
Metabolism Research
Smiles
C (N1C=2N (C (=NN2) C3=CC (C (O) =O) =CC=C3O) C=4C (C1=O) =CC=CC4) C5=C (Cl) C=CC=C5
Molecular Formula
C23H15ClN4O4
Molecular Weight
446.84
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-[4-(2-Chlorobenzyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl]-4-hydroxybenzoic Acid
CAS Number2222280-83-1
PubChem CID137349219
IUPAC Name3-[4-[(2-chlorophenyl)methyl]-5-oxo-[1,2,4]triazolo[4,3-a]quinazolin-1-yl]-4-hydroxybenzoic acid
Molecular FormulaC23H15ClN4O4
Molecular Weight446.8
XLogP3.5
Topological Polar Surface Area109
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity726
SMILES
C1=CC=C(C(=C1)CN2C(=O)C3=CC=CC=C3N4C2=NN=C4C5=C(C=CC(=C5)C(=O)O)O)Cl
InChI
InChI=1S/C23H15ClN4O4/c24-17-7-3-1-5-14(17)12-27-21(30)15-6-2-4-8-18(15)28-20(25-26-23(27)28)16-11-13(22(31)32)9-10-19(16)29/h1-11,29H,12H2,(H,31,32)
InChIKey
AEJITBHMBLVYPB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-[4-(2-Chlorobenzyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl]-4-hydroxybenzoic Acid
CAS: 2222280-83-1
CID: 137349219
Formula: C23H15ClN4O4
MW: 446.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight446.8
XLogP33.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass446.0781827
Monoisotopic Mass446.0781827
Topological Polar Surface Area109 Ų
Heavy Atom Count32
Formal Charge0
Complexity726
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19211680-01SHP244
GTR19203103-01SHP394
GTR19212074-01SHP844

Alternative Products

CatalogName
MBS5805337SHP504

Popular Products