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15 (S) -HEDE

CAT: 0804-HY-121987Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121987Size:1 Each
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Description
15 (S) -HEDE (Compound 8) is an analogue of 15-HEDE that inhibits 5-lipoxygenase with an IC50 value of 26 μM. 15 (S) -HEDE is promising for research of inflammatory disease[1].
CAS Number
92693-04-4
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/15-s-hede.html
Smiles
OC(CCCCCCCCC/C=C\C=C\[C@@H](O)CCCCC)=O
Molecular Formula
C20H36O3
Molecular Weight
324.50
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Haviv F, et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J Med Chem. 1987 Feb;30 (2) :254-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported