15(S)-HpEPE

15(S)-HpEPE

• CAS Number: 125992-60-1
• UNSPSC Description: 15(S)-HpEPE is a product of lipoxygenase hydrolysis of unsaturated fatty acids (PUFA) and is a potential inhibitor of prostaglandin H synthase 2 (PGHS-2). 15(S)-HpEPE can downregulate the expression of PGHS-2[1].
• Target Antigen: Prostaglandin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/15-s-hpepe.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)C/C=C\CC)=O
• Molecular Weight: 334.45
• References & Citations: [1]Ait-Said F, et al. Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta. 2003 Feb 20;1631(1):77-84.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported