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A1AT modulator 2

CAT: 0804-HY-134863-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-134863-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of > 1.0 μM and an EC50 value of [1].
CAS Number
2555004-05-0
UNSPSC
12352005
Target
Serpin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a1at-modulator-2.html
Purity
98.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(C2=C(C3CCOCC3)N(C4=CC=C(F)C=C4)C5=CC6=C(NN=C6)C=C52)C=C1
Molecular Formula
C27H22FN3O3
Molecular Weight
455.48
References & Citations
[1]Bandarage, Upul Keerthi, et al. Pyrrolo[2,3-f]indazole derivatives as modulators of α-1 antitrypsin and their preparation. US20200361939. 2020.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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