A1AT modulator 2

• Description :

  A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of > 1.0 μM and an EC50 value of [1].

• UNSPSC :

  12352005

• Target :

  Serpin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/a1at-modulator-2.html

• Purity :

  98.32

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C1=CC=C(C2=C(C3CCOCC3)N(C4=CC=C(F)C=C4)C5=CC6=C(NN=C6)C=C52)C=C1

• Molecular Formula :

  C27H22FN3O3

• Molecular Weight :

  455.48

• References & Citations :

  [1]Bandarage, Upul Keerthi, et al. Pyrrolo[2,3-f]indazole derivatives as modulators of α-1 antitrypsin and their preparation. US20200361939. 2020.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2555004-05-0]