ISPA-28

• Description :

  ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3[1][2].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ispa-28.html

• Concentration :

  10mM

• Purity :

  99.75

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1CC(C2=CN(CC)N=C2C)=NO1)NC3=C(C)N(C)N(C4=CC=CC=C4)C3=O

• Molecular Formula :

  C21H24N6O3

• Molecular Weight :

  408.45

• References & Citations :

  [1]Sanjay A Desai, et al. Ion and Nutrient Uptake by Malaria Parasite-Infected Erythrocytes.|[2]Wang Nguitragool, et al. Proteolysis at a Specific Extracellular Residue Implicates Integral Membrane CLAG3 in Malaria Parasite Nutrient Channels.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [1006335-39-2]