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2,3-Diaminophenazine

CAT: 0804-HY-W020086Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W020086Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,3-Diaminophenazine (2,3-Phenazinediamine) is an orally active amino derivative of phenazine. 2,3-Diaminophenazine can intercalate into DNA. 2,3-Diaminophenazine triggers photochemical reactions. 2,3-Diaminophenazine inhibits vascular hypertrophy and tissue AGE deposition in diabetic rats. 2,3-Diaminophenazine can be used for luminescence and diabetes research[1][2][3][4].
CAS Number
655-86-7
Product Name Alternative
2,3-Phenazinediamine; NNC39-0028
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-3-diaminophenazine.html
Purity
99.84
Solubility
DMSO : 5.83 mg/mL (ultrasonic)
Smiles
NC1=CC2=NC3=CC=CC=C3N=C2C=C1N
Molecular Formula
C12H10N4
Molecular Weight
210.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Xiaoyue He, et al. Selective self-assembly of 2,3-diaminophenazine molecules on MoSe 2 mirror twin boundaries. Nat Commun. 2019 Jun 28;10 (1) :2847.|[2]Feng Zhang, et al. An enzymatic ratiometric fluorescence assay for 6-mercaptopurine by using MoS 2 quantum dots. Mikrochim Acta. 2018 Nov 10;185 (12) :540.|[3]Fu PK, et al. Photoinduced DNA cleavage and cellular damage in human dermal fibroblasts by 2,3-diaminophenazine. Photochem Photobiol. 2005 Jan-Feb;81 (1) :89-95.|[4]Soulis T, et al. A novel inhibitor of advanced glycation end-product formation inhibits mesenteric vascular hypertrophy in experimental diabetes. Diabetologia. 1999 Apr;42 (4) :472-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported