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14-3-3-IN-2

CAT: 0804-HY-177590-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-177590-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
14-3-3-IN-2 is a 14-3-3 protein inhibitor with an IC50 of 15 nM. 14-3-3-IN-2 can disrupt the interaction of 14-3-3α with aminopeptidase N and down-regulate 14-3-3α increased MMP-1 mRNA levels[1].
CAS Number
919751-10-3
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
98.41
Smiles
O=C(COC1=C(P(O)(O)=O)C=CC=C1)NC2CCCCC2
Molecular Formula
C14H20NO5P
Molecular Weight
313.29
References & Citations
[1]Thiel P, et al. Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem Commun (Camb) . 2013 Oct 4;49 (76) :8468-70.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-1

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Alternative Products

CatalogName
GTR19273413-0114-3-3-IN-2
sc-51803114-3-3 ζ (G-2)
50639414-3-3 (14-3-3 Protein Theta, 14-3-3) discontinued
sc-518031 PE14-3-3 ζ (G-2) PE
GTR19275066-0114-3-3σ/ERα stabilizer-2
sc-518031 HRP14-3-3 ζ (G-2) HRP
sc-518031 AC14-3-3 ζ (G-2) AC
sc-518031 FITC14-3-3 ζ (G-2) FITC
MBS8534245-0114-3-3
220455-0114-3-3 theta (14-3-3 Protein theta, 14-3-3 Protein T-Cell, 14-3-3 Protein tau, Protein HS1, YWHAQ, 14-3-3 θ, 14-3-3 τ, 1433T) discontinued

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