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MBQ-167

CAT: 0804-HY-112842-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112842-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively.
CAS Number
2097938-73-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK; Ras
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MBQ-167.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCN1C2=C(C3=C1C=CC=C3)C=C(N4N=NC=C4C5=CC=CC=C5)C=C2
Molecular Formula
C22H18N4
Molecular Weight
338.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Humphries-Bickley T, et al. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer. Mol Cancer Ther. 2017 May;16 (5) :805-818.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CDC

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Alternative Products

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XID93873-01MBQ-167
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A16808-50MBQ-167 50mg
A16808-25MBQ-167 25mg
A16808-10MBQ-167 10mg
A16808-1MBQ-167 1mg
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