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GRK2 degrader-1

CAT: 0013-GTR19281082-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19281082-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GRK2 degrader-1 (compound 1) is a potent and orally active GRK2 degrader. It facilitates the degradation of GRK2 via the ubiquitin-proteasome pathway. In a pulmonary arterial hypertension (PAH) mouse model, GRK2 degrader-1 inhibits right ventricular remodeling and the increase in pulmonary arterial pressure. This compound is suitable for research in pulmonary arterial hypertension (PAH) .
CAS Number
3052947-04-0
Smiles
O=C (NC1=NC=C (S1) CC=2C=CC=CC2) CC3=CC=C4C (=C3) C (=O) N (C4) C5C (=O) NC (=O) CC5
Molecular Formula
C25H22N4O4S
Molecular Weight
474.54
Notes
For research use only.

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