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Nrf2 degrader 1

CAT: 0013-GTR19234873-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234873-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nrf2 degrader 1 (compound 1) is a potent PROTAC molecule that induces Nrf2 degradation, demonstrating anticancer activity with IC50 values of 100 nM in A549 cells and 40 nM in LK-2 cells. It is a valuable research tool for studying Nrf2's role in cancer cell proliferation and chemoresistance in vitro.
CAS Number
3025286-00-1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOC4=CC (CC (NC5=NC (=C (C) S5) C=6C=C7C (=CC6) N (C (=O) C8=C (C) C=CC=C8) CC7) =O) =CC=C4
Molecular Formula
C45H42N6O8S
Molecular Weight
826.92
Storage Conditions
-20°C
Notes
For research use only.

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